A Short History of Bipolar

A Short History of Bipolar

The terms used for the bipolar extremes, ‘melancholy’ (depression) and ‘mania’ both have their origins in Ancient Greek. ‘Melancholy’ derives from melas ‘black’ and chole ‘bile’, because Hippocrates thought that depression resulted from an excess of black bile. ‘Mania’ is related to menos ‘spirit, force, passion’; mainesthai ‘to rage, go mad’; and mantis ‘seer’, and ultimately derives from the Indo-European root men- ‘mind’ to which, interestingly, ‘man’ is also sometimes connected. (‘Depression’, the clinical term for melancholy, is much more recent in origin and derives from the Latin deprim... »

Body clock may hold key for BD treatment

Body clock may hold key for BD treatment

Scientists have gained insight into why lithium salts are effective at treating bipolar disorder in what could lead to more targeted therapies with fewer side-effects. Bipolar disorder is characterised by alternating states of elevated mood, or mania, and depression. It affects between 1 and 3 per cent of the general population. The extreme ‘mood swings’ in bipolar disorder have been strongly associated with disruptions in circadian rhythms – the 24-hourly rhythms controlled by our body clocks that govern our day and night activity. For the last 60 years, lithium salt (lithium chlo... »

Benefits of Bipolar Disorder?

Benefits of Bipolar Disorder?

Some individuals with bipolar disorder say they experience highly-valued, positive experiences from living with the condition, according to new research by Lancaster University. According to the study, ten people (ages 24 to 57) with bipolar disorder reported several perceived benefits in having the condition, which included having sharper senses and increased productivity. For the study, researchers set out to investigate growing evidence that some people with bipolar value certain experiences the disorder brings, and in some cases, would prefer to keep the condition. Study participants descr... »

DBS Appears Effective For Bipolar Disorder

DBS Appears Effective For Bipolar Disorder

A new study shows that deep brain stimulation (DBS) is a safe and effective intervention for treatment-resistant depression. The study, led by researchers at Emory University in Atlanta, found that DBS works in patients with either unipolar major depressive disorder or bipolar II disorder. “Depression is a serious and debilitating medical illness,” says Helen S. Mayberg, MD, a professor in the Departments of Psychiatry and Behavioral Sciences, Neurology and Radiology at Emory University School of Medicine, who led the study. “When we found that the potential for effective and sustained antidep... »